Impact Case Studies
At the MCRC, we’re committed to delivering impactful research that influences the scientific and clinical delivery of cancer research. We aim for our research to have a positive impact on healthcare and cancer research the world over, and how we impact policy, clinical practice, research protocol and patients’ lives.
We are proud of our research and below you will discover a selection of case studies that demonstrate our World-Leading, Practice-Influencing, Life-Changing and Team-Building cancer research activities.
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Impact Case Study
Pseudomyxoma peritonei (PMP)
This impact case study covers three areas in which our team in Manchester have progressed the understanding of AMNs as tumours and PMP as a disease.
Impact Case Study
BRAINatomy 1
Read about BRAINatomy which was led by The University of Manchester in collaboration with The Christie NHS Foundation Trust to improve the outcomes for children diagnosed with brain tumours. This project used large “real-world” datasets to learn how to develop kinder treatments, providing information about how to safely change radiotherapy planning practice.
Impact Case Study
Penile cancer
Read about a systematic review examining the clinical evidence for lymph node-positive penile cancer which has led to changes in treatment guidelines and an Impact Award for our team at The Christie and The University of Manchester. The review has since helped inform current clinical decision making and has been used to develop updated 2023 EAU-ASCO penile cancer guidelines.
Impact Case Study
Changing clinical practice for patients with Lymphoma
Impact Case Study
The Case for Banning Sunbeds
A multi-disciplinary team of researchers across Manchester and Australia have been working to assess the cost-effectiveness of this policy-based intervention in reducing the burden of skin cancer on the NHS.
Impact Case Study
PROCAS 2
Impact Case Study
PROCAS and BC-PREDICT
We speak to Professor Gareth Evans about how the findings from PROCAS 1 led to the inception of PROCAS 2, which assesses the feasibility of implementing a personalised risk score into a woman’s first screening appointment and the associated impact on NHS staff, patients and other related organisations.
Impact Case Study
Changing National Healthcare Guidance – A Lynch Syndrome Example
Impact Case Study
Low-grade appendiceal mucinous neoplasms and Pseudomyxoma peritonei
The MCRC Biobank team secured the CRUK accelerator award and are working alongside four centres across the UK, Italy and Spain to collect samples from patients with PMP to better understand the nature of these tumours.
Impact Case Study
Improving the standard of care for biliary tract cancers around the world
Impact Case Study
Identifying genetic variation of prostate cancer in Kenya: A move towards healthcare equality
David Wedge is carrying out research to identify what mutations occur in Kenyan men with the aim of identifying if these are caused by environmental factors or inherited genes
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