PROSTATE CANCER

 

WHERE TO FIND US

• The Christie NHS Foundation Trust
• MCRC building
• CRUK MI
• Salford Royal NHS Foundation Trust

The focus for our prostate cancer research is the FASTMAN Movember Centre of Excellence, which unites both hospital and research laboratory across two cities: Manchester and Belfast.

KEY PUBLICATIONS

The Evolutionary Landscape of Localized Prostate Cancers Drives Clinical Aggression.
Espiritu SMG, Liu LY, Rubanova Y, Bhandari V, Holgersen EM, Szyca LM, Fox NS, Chua MLK, Yamaguchi TN, Heisler LE, Livingstone J, Wintersinger J, Yousif F, Lalonde E, Rouette A, Salcedo A, Houlahan KE, Li CH, Huang V, Fraser M, van der Kwast T, Morris QD, Bristow RG, Boutros PC.
Cell. 2018 May 3;173(4):1003-1013.e15. doi: 10.1016/j.cell.2018.03.029. 

Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer.
Yang L, Roberts D, Takhar M, Erho N, Bibby BAS, Thiruthaneeswaran N, Bhandari V, Cheng WC, Haider S, McCorry AMB, McArt D, Jain S, Alshalalfa M, Ross A, Schaffer E, Den RB, Jeffrey Karnes R, Klein E, Hoskin PJ, Freedland SJ, Lamb AD, Neal DE, Buffa FM, Bristow RG, Boutros PC, Davicioni E, Choudhury A, West CML.
EBioMedicine. 2018 Apr 23. pii: S2352-3964(18)30147-6. doi: 10.1016/j.ebiom.2018.04.019. 

Influence of an International Consensus Conference on Practice Patterns in Advanced Prostate Cancer.
Gong J, Omlin A, Pal SK, Hsu J, Tombal B, Sydes MR, Gillessen S.
Eur Urol. 2018 May 3. pii: S0302-2838(18)30330-0. doi: 10.1016/j.eururo.2018.04.024.

Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017.
Gillessen S, Attard G, Beer TM, Beltran H, Bossi A, Bristow R, Carver B, Castellano D, Chung BH, Clarke N, Daugaard G, Davis ID, de Bono J, Borges Dos Reis R, Drake CG, Eeles R, Efstathiou E, Evans CP, Fanti S, Feng F, Fizazi K, Frydenberg M, Gleave M, Halabi S, Heidenreich A, Higano CS, James N, Kantoff P, Kellokumpu-Lehtinen PL, Khauli RB, Kramer G, Logothetis C, Maluf F, Morgans AK, Morris MJ, Mottet N, Murthy V, Oh W, Ost P, Padhani AR, Parker C, Pritchard CC, Roach M, Rubin MA, Ryan C, Saad F, Sartor O, Scher H, Sella A, Shore N, Smith M, Soule H, Sternberg CN, Suzuki H, Sweeney C, Sydes MR, Tannock I, Tombal B, Valdagni R, Wiegel T, Omlin A.
Eur Urol. 2018 Feb;73(2):178-211. doi: 10.1016/j.eururo.2017.06.002. 

Primary Mutational Landscape Linked with Pre-Docetaxel Lactate Dehydrogenase Levels Predicts Docetaxel Response in Metastatic Castrate-Resistant Prostate Cancer.
Hiew K, Hart CA, Ali A, Elliott T, Ramani V, Sangar V, Lau M, Maddineni S, Brown M, Clarke N.
Eur Urol Focus. 2018 Apr 23. pii: S2405-4569(18)30096-8. doi: 10.1016/j.euf.2018.04.006.

WHO'S WHO

Biology

Medical Oncology

  • Silke Gillessen

Clinical Oncology

Urology